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Article

Salicylic acid activates sigma factor B by rsbU-dependent and -independent mechanisms.

Journal of bacteriology - 1 Aug 2006

Palma Marco, Bayer Arnold, Kupferwasser Leon I, Joska Tammy, Yeaman Michael R, Cheung Ambrose

Abstract excerpt

Salicylic acid (SAL) may impact Staphylococcus aureus virulence by activating the sigB operon (rsbU-V-W-sigB), thus leading to reductions in alpha-toxin production and decreased fibronectin binding (L. I. Kupferwasser et al., J. Clin. Investig. 112:222-233, 2003). As these prior studies were performed in strain RN6390 (an rsbU mutant) and its rsbU-repaired variant, SH1000, the current investigation was designed...

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Identifiers

PMID: 16885458
DOI: 10.1128/JB.01960-05
PMCID: PMC1540054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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