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Salicylic acid stabilizes Staphylococcus aureus biofilm by impairing the agr quorum-sensing system

3 Feb 2021

Abstract excerpt

Salicylic acid (SAL) has recently been shown to induce biofilm formation in Staphylococcus aureus and to affect the expression of virulence factors. This study was aimed to investigate the effect of SAL on the regulatory agr system and its impact on S. aureus biofilm formation. The agr quorum-sensing system, which is a central regulator in S. aureus pathogenicity, plays a pivotal role in the dispersal of S....

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PMID: 33536503
DOI: 10.1038/s41598-021-82308-y

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