Article
Sigma(B) activity depends on RsbU in Staphylococcus aureus.
Journal of bacteriology - 1 Mar 2001
Giachino P, Engelmann S, Bischoff M
Abstract excerpt
Derivatives of the widely used laboratory strain Staphylococcus aureus NCTC8325, which are natural rsbU mutants, were shown to be unable to produce RsbU, a positive regulator of the alternative sigma factor sigma(B). The lack of RsbU prevented the heat-dependent production of sigma(B)-controlled transcripts and resulted in reduced H2O2 and UV tolerance, enhanced alpha-hemolysin activity, and the inability to...
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