Article
Comparing isoflurane with tribromoethanol anesthesia for echocardiographic phenotyping of transgenic mice.
Journal of the American Association for Laboratory Animal Science : JAALAS - 1 Jul 2006
Chu David K, Jordan Maria C, Kim Jeanne K, Couto Marcelo A, Roos Kenneth P
Abstract excerpt
Cardiac phenotyping of transgenic mice typically requires anesthesia. Chemical-grade tribromoethanol (TBE) is commonly used for this purpose due to its relatively short duration of action, modest cardiodepressive effects, and its noncontrolled status. In the present study, we used both genders of C57BL/6;C3H-Tg(Slc8a1)hKdp transgenic (TG) mice and C57BL/6;C3H wild-type (WT) mice to evaluate isoflurane (ISF) as a...
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