Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apoptosis in the developing mouse heart

31 Jul 2006

Abstract excerpt

Apoptosis occurs at high frequency in the myocardium of the developing avian cardiac outflow tract (OFT). Up- or down-regulating apoptosis results in defects resembling human conotruncal heart anomalies. This finding suggested that regulated levels of apoptosis are critical for normal morphogenesis of the four-chambered heart. Recent evidence supports an important role for hypoxia of the OFT myocardium in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital heart defects research
Share to Congenital Heart Disease Studies
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16881058
DOI: 10.1002/dvdy.20885

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Apoptosis in the developing mouse heartPMID 16881058Read ↗

Programmed cell death in the developing heart: Regulation by BMP4 and FGF2Semantic proximity Read ↗

Developmental remodeling and shortening of the cardiac outflow tract involves myocyte programmed cell deathSemantic proximity Read ↗

NORMAL AND ABNORMAL CONSEQUENCES OF APOPTOSIS IN THE HUMAN HEARTSemantic proximity Read ↗

Septation and shortening of outflow tract in embryonic mouse heart involve changes in cardiomyocyte phenotype and alpha-SMA positive cells in the endocardium.Semantic proximity Read ↗

Apoptosis as an instrument in cardiovascular developmentSemantic proximity Read ↗

Histology Atlas of the Developing Mouse Heart with Emphasis on E11.5 to E18.5Semantic proximity Read ↗

Double-outlet right ventricle and overriding tricuspid valve reflect disturbances of looping, myocardialization, endocardial cushion differentiation, and apoptosis in TGF-beta(2)-knockout mice.Semantic proximity Read ↗

Overlapping and differential localization of Bmp-2, Bmp-4, Msx-2 and apoptosis in the endocardial cushion and adjacent tissues of the developing mouse heartSemantic proximity Read ↗

Limited Regeneration Potential with Minimal Epicardial Progenitor Conversions in the Neonatal Mouse Heart after InjurySemantic proximity Read ↗

Myocyte apoptosis in heart failureSemantic proximity Read ↗

Myocardin is differentially required for the development of smooth muscle cells and cardiomyocytesSemantic proximity Read ↗

Endocardial-mesenchymal transition underlies fusion of the conotruncal ridges during normal and bicuspid aortic valve developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.