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Programmed cell death in the developing heart: Regulation by BMP4 and FGF2

1 Apr 2000

Abstract excerpt

Programmed cell death, or apoptosis, plays an important role in embryonic development. To provide new insights into the role of programmed cell death in cardiac development, we examined the hearts of the murine embryos from E9.5 to postnatal day 3. Using terminal transferase-mediated dUTP nick end-labeling assays, apoptosis was detected in the endocardial cushions and myocardium from E11.5 to postnatal day 3...

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PMID: 10767083
DOI: 10.1002/(sici)1097-0177(200004)217:4<388::aid-dvdy6>3.0.co;2-n

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