Article
Polymorphisms of the apolipoprotein B and E genes and their possible roles in familial and non-familial combined hyperlipidaemia.
Disease markers - 1 Jan 2000
Houlston R, Lewis B, Humphries S E
Abstract excerpt
The frequency of polymorphisms of the apolipoprotein (apo) B and E gene loci were studied in 59 patients with primary combined hyperlipidaemia, including 26 with familial combined hyperlipidaemia. Variation at the apo B gene locus was examined using restriction enzymes XbaI, EcoRI, and PvuII. At...
Topics
- Adult
- Aged
- Alleles
- Apolipoproteins B
- Apolipoproteins E
- Female
- Gene Frequency
- Genetic Markers
- Genotype
- Humans
- Hyperlipidemia, Familial Combined
- Hyperlipidemias
- Male
- Middle Aged
- Polymorphism, Restriction Fragment Length
