Article
Variation in the apolipoprotein B gene and development of type 2 diabetes mellitus.
Disease markers - 1 Jan 2000
Houlston R S, Snowden C, Laker M F, Alberti K G, Humphries S E
Abstract excerpt
Several studies have demonstrated an association between variation in the apolipoprotein (apo) B gene, principally as detected by the XbaI and EcoRI restriction fragment length polymorphisms (RFLPs), and lipoprotein levels or cardiovascular disease. We have examined the frequency of the EcoRI and XbaI RFLPs of the apoB gene in 95 white Type 2 diabetic patients aged between 45 and 80 years in order to ascertain...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Apolipoproteins B
- Autoradiography
- Diabetes Mellitus, Type 2
- Diabetic Angiopathies
- Genes
- Humans
- Middle Aged
- Polymorphism, Restriction Fragment Length
