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Article

Interaction of beta2-glycoprotein I with members of the low density lipoprotein receptor family.

Journal of thrombosis and haemostasis : JTH - 1 Aug 2006

Pennings M T T, van Lummel M, Derksen R H W M, Urbanus R T, Romijn R A, Lenting P J, de Groot P G

Abstract excerpt

The antiphospholipid syndrome (APS) is a non-inflammatory autoimmune disease characterized by arterial and/or venous thrombosis and/or pregnancy morbidity in the presence of autoantibodies that recognize beta2-glycoprotein I (beta2GPI) bound to phospholipids. We have previously demonstrated that dimerization of beta2GPI by autoantibodies induces platelet activation, involving the platelet receptor apolipoprotein...

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Identifiers

PMID: 16879209
DOI: 10.1111/j.1538-7836.2006.02036.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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