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Article

Role of the covalent flavin linkage in monomeric sarcosine oxidase.

Biochemistry - 8 Aug 2006

Hassan-Abdallah Alshaimaa, Zhao Guohua, Jorns Marilyn Schuman

Abstract excerpt

Monomeric sarcosine oxidase (MSOX) is a prototypical member of a recently recognized family of amine-oxidizing enzymes that all contain covalently bound flavin. Mutation of the covalent flavin attachment site in MSOX produces a catalytically inactive apoprotein (apoCys315Ala) that forms an unstable complex with FAD (K(d) = 100 muM), similar to that observed with wild-type apoMSOX where the complex is formed as an...

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PMID: 16878980
DOI: 10.1021/bi0607352

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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