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Article

Intramolecular electron transfer in sulfite-oxidizing enzymes: probing the role of aromatic amino acids.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry - 1 Mar 2012

Rajapakshe Asha, Meyers Kimberly T, Berry Robert E, Tollin Gordon, Enemark John H

Abstract excerpt

Sulfite oxidase (SO) is a molybdoheme enzyme that is important in sulfur catabolism, and mutations in the active site region are known to cause SO deficiency disorder in humans. This investigation probes the effects that mutating aromatic residues (Y273, W338, and H337) in the molybdenum-containing domain of human SO have on both the intramolecular electron transfer (IET) rate between the molybdenum and iron...

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Identifiers

PMID: 22057690
DOI: 10.1007/s00775-011-0856-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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