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Article

Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects.

Diabetes - 1 Aug 2006

Yokoi Norihide, Kanamori Masao, Horikawa Yukio, Takeda Jun, Sanke Tokio, Furuta Hiroto, Nanjo Kishio, Mori Hiroyuki, Kasuga Masato, Hara Kazuo, Kadowaki Takashi, Tanizawa Yukio, Oka Yoshitomo, Iwami Yukiko, Ohgawara Hisako, Yamada Yuichiro, Seino Yutaka, Yano Hideki, Cox Nancy J, Seino Susumu

Abstract excerpt

Because impaired insulin secretion is characteristic of type 2 diabetes in Asians, including Japanese, the genes involved in pancreatic beta-cell function are candidate susceptibility genes for type 2 diabetes. We examined the association of variants in genes encoding several transcription factors (TCF1, TCF2, HNF4A, ISL1, IPF1, NEUROG3, PAX6, NKX2-2, NKX6-1, and NEUROD1) and genes encoding the ATP-sensitive K(+)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16873704
DOI: 10.2337/db05-1203

Genes

ABCC8
KCNJ11
ISL1
NEUROD1
NEUROG3
PAX6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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