Article
Genomes of Helicobacter pylori from native Peruvians suggest admixture of ancestral and modern lineages and reveal a western type cag-pathogenicity island.
BMC genomics - 27 Jul 2006
Devi S Manjulata, Ahmed Irshad, Khan Aleem A, Rahman Syed Asad, Alvi Ayesha, Sechi Leonardo A, Ahmed Niyaz
Abstract excerpt
BACKGROUND: Helicobacter pylori is presumed to be co-evolved with its human host and is a highly diverse gastric pathogen at genetic levels. Ancient origins of H. pylori in the New World are still debatable. It is not clear how different waves of human migrations in South America contributed to t...
Topics
- Antigens, Bacterial
- Bacterial Proteins
- Base Sequence
- Chromosome Mapping
- Genome, Bacterial
- Genomic Islands
- Genotype
- Helicobacter pylori
- Humans
- Japan
- Models, Biological
- Molecular Sequence Data
- Nucleic Acid Amplification Techniques
- Peru