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Article

The cag pathogenicity island of Helicobacter pylori is disrupted in the majority of patient isolates from different human populations.

Journal of clinical microbiology - 1 Nov 2004

Kauser Farhana, Khan Aleem A, Hussain M Abid, Carroll Ian M, Ahmad Naheed, Tiwari Santosh, Shouche Yogesh, Das Bimal, Alam Mahfooz, Ali S Mahaboob, Habibullah C M, Sierra Rafaela, Megraud Francis, Sechi Leonardo A, Ahmed Niyaz

Abstract excerpt

The cag pathogenicity island (cag-PAI) is one of the major virulence determinants of Helicobacter pylori. The chromosomal integrity of this island or the lack thereof is speculated to play an important role in the progress of the gastroduodenal pathology caused by H. pylori. We determined the integrity of the cag-PAI by using specific flanking and internally anchored PCR primers to know the biogeographical...

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Identifiers

PMID: 15528729
DOI: 10.1128/JCM.42.11.5302-5308.2004
PMCID: PMC525253

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Source receipt: pubmed, retrieved 7 Sept 2026.

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