Article
The cag pathogenicity island of Helicobacter pylori is disrupted in the majority of patient isolates from different human populations.
Journal of clinical microbiology - 1 Nov 2004
Kauser Farhana, Khan Aleem A, Hussain M Abid, Carroll Ian M, Ahmad Naheed, Tiwari Santosh, Shouche Yogesh, Das Bimal, Alam Mahfooz, Ali S Mahaboob, Habibullah C M, Sierra Rafaela, Megraud Francis, Sechi Leonardo A, Ahmed Niyaz
Abstract excerpt
The cag pathogenicity island (cag-PAI) is one of the major virulence determinants of Helicobacter pylori. The chromosomal integrity of this island or the lack thereof is speculated to play an important role in the progress of the gastroduodenal pathology caused by H. pylori. We determined the int...
Topics
- Antigens, Bacterial
- Asia
- Bacterial Proteins
- Costa Rica
- Europe
- Gene Deletion
- Genotype
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Polymerase Chain Reaction
- South Africa
- Virulence