Article
Prevention of rifampicin resistance in Acinetobacter baumannii in an experimental pneumonia murine model, using rifampicin associated with imipenem or sulbactam.
The Journal of antimicrobial chemotherapy - 1 Sept 2006
Pachón-Ibáñez María E, Fernández-Cuenca Felipe, Docobo-Pérez Fernando, Pachón Jerónimo, Pascual Alvaro
Abstract excerpt
OBJECTIVES: To examine the development of rifampicin resistance in multidrug-resistant Acinetobacter baumannii exposed to rifampicin and the prevention of the appearance of rifampicin-resistant mutants when rifampicin is used in association with imipenem or sulbactam. METHODS: A clinical strain of multidrug-resistant A. baumannii was used to examine the frequency of resistance to rifampicin in vivo, in a...
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