Article
Genetic association between USF 1 and USF 2 gene polymorphisms and Japanese Alzheimer's disease.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Jul 2006
Shibata Nobuto, Ohnuma Tohru, Higashi Shinji, Higashi Maiko, Usui Chie, Ohkubo Taku, Watanabe Tomoko, Kawashima Ritsuko, Kitajima Akiyoshi, Ueki Akira, Nagao Masatsugu, Arai Heii
Abstract excerpt
To investigate the effect of single nucleotide polymorphisms (SNPs) of the upstream stimulatory factor (USF) 1 and 2 genes on the onset of Alzheimer's disease (AD), a case-control study was performed. The SNPs were genotyped by a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method in 236 AD patients and 120 age-matched controls of Japanese descent. We observed no significant...
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