Article
Association of tumor necrosis factor-alpha and interleukin-10 gene polymorphisms in Iranian patients with pre-eclampsia.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Aug 2008
Mirahmadian Mahroo, Kalantar Fathollah, Heidari Golnaz, Safdarian Lili, Mansouri Reza, Amirzargar Ali Akbar
Abstract excerpt
PROBLEM: Considering that certain cytokines may change during pre-eclampsia (PE), because of functional polymorphisms in their genes, our purpose was to determine the association between tumor necrosis factor-alpha (TNF-alpha) and interleukin-10 (IL-10) gene polymorphisms and development of PE. METHOD OF STUDY: The genetic polymorphisms of TNF-alpha and IL-10 was studied by polymerase chain reaction-sequence...
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