Article
Cytokine gene polymorphisms in preeclampsia and eclampsia.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jul 2009
de Lima Telmo H Barbosa, Sass Nelson, Mattar Rosiane, Moron Antonio F, Torloni Maria R, Franchim Camila S, Daher Silvia
Abstract excerpt
The clinical spectrum of preeclampsia (PE) ranges from mild hypertension to severe vasospasm associated with convulsions and multiple organ damage. The biological factors that determine the progression of PE to eclampsia (E) are unknown. Endothelial cell activation seems related to an impaired maternal immune response. The production of cytokines, IL-10 and TGF-beta1, is apparently suppressed, and altered...
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