Article
<i>EGFR</i> point mutation in non‐small cell lung cancer is occasionally accompanied by a second mutation or amplification
9 Jun 2006
Abstract excerpt
Activating mutations of EGFR are found frequently in a subgroup of patients with non-small cell lung cancer (NSCLC) and are highly correlated with the response to gefitinib and erlotinib. In the present study, we searched for mutations of EGFR, HER2 and KRAS in 264 resected primary NSCLC from Japanese patients and determined whether there is a correlation between genetic alterations of these genes and...
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