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Article

R-Ras promotes metastasis of cervical cancer epithelial cells.

Cancer immunology, immunotherapy : CII - 1 Apr 2007

Mora Nancy, Rosales Ricardo, Rosales Carlos

Abstract excerpt

Mutations in the small GTPase R-Ras that promote constitutive activation of this signaling molecule have been observed in a variety of invasive cancer cell types. We previously reported that expression of an oncogenic form of R-Ras (R-Ras87L) in a cell line of cervical cancer (C33A cells) augments cell growth in vitro and tumorigenicity in vivo. Because increased tumorigenicity in vivo often precedes metastasis,...

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Identifiers

PMID: 16862428
DOI: 10.1007/s00262-006-0205-z
PMCID: PMC11031036

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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