Article
Characterization of copper-inducible promoters regulated by CpxA/CpxR in Escherichia coli.
Bioscience, biotechnology, and biochemistry - 1 Jul 2006
Yamamoto Kaneyoshi, Ishihama Akira
Abstract excerpt
The copper stimulon in Escherichia coli consists of four regulons, the CueR-, CusS/CusR-, CpxA/CpxR-, and YedV/YedW regulons. E. coli mutants defective in cpxRA showed higher sensitivity to copper than the wild type. A total of 15 promoters were found to be induced in E. coli culture upon exposure to copper in a CpxA/CpxR-dependent manner. After gel-shift and DNase I foot-printing analyses, a conserved tandem...
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