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Article

Neutralizing epitopes in the membrane-proximal region of HIV-1 gp41: genetic variability and co-variation.

Immunology letters - 15 Aug 2006

Dong Xiao-Nan, Chen Ying-Hua

Abstract excerpt

Recent investigations on the passive immunization have proved that neutralizing antibodies directed to the membrane-proximal region of HIV-1 gp41 are potent anti-viral components, so this region is thought to be an attractive target for AIDS vaccine. Three key neutralizing epitopes, ELDKWA (aa662-667), NWFDIT (aa671-676) and ERDRDR (aa739-744) have been mapped in this region. In this study, their genetic...

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Identifiers

PMID: 16859756
DOI: 10.1016/j.imlet.2006.06.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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