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Article

Association of variations of NAb 2F5 and 4E10 epitopes and disease progression in Chinese antiretroviral treatment-naïve patients infected with HIV-1 clade B'.

Chinese medical journal - 1 Dec 2010

Zhang Xiao-Li, Han Xiao-Xu, Dai Di, Bao Ming-Jia, Xu Dong-Bing, Zhang Zi-Ning, Wang Ya-Nan, Zhao Min, Bice Tristan, Jiang Yong-Jun, Shang Hong

Abstract excerpt

BACKGROUND: Studies on human immunodeficiency virus type 1 (HIV-1) vaccines have recently focused on targeting the conserved neutralizing epitopes 2F5 and 4E10, and hence it is important to understand the extent of mutations in these two viral epitopes. Here, we investigated the amino acid mutations in epitopes of 2F5 (ELDKWA, HIV-1 HXB2 env 662 - 667 aa) and 4E10 (NWFDIT, HIV-1 HXB2 env 671 - 676 aa) in the...

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Share to Acquired Immunodeficiency Syndrome
Share to Antibodies, Neutralizing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epitopes

Share to HIV Antibodies

Share to HIV Envelope Protein gp41

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Identifiers

PMID: 22166522

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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