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Article

A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1

1 Nov 1993

Abstract excerpt

Vaccination against human immunodeficiency virus type 1 (HIV-1) requires an immunogen which will elicit a protective immunity against viruses that show a high degree of genetic polymorphism. Therefore, the identification of neutralizing epitopes which are shared by many strains would be useful. In previous studies, we established a human monoclonal antibody (2F5) that neutralizes a variety of laboratory strains...

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Identifiers

PMID: 7692082
DOI: 10.1128/jvi.67.11.6642-6647.1993

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