Article
The CD14 functional gene polymorphism -260 C>T is not involved in either the susceptibility to Chlamydia trachomatis infection or the development of tubal pathology.
BMC infectious diseases - 20 Dec 2005
Ouburg Sander, Spaargaren Joke, den Hartog Janneke E, Land Jolande A, Fennema Johan S A, Pleijster Jolein, Peña A Salvador, Morré Servaas A
Abstract excerpt
BACKGROUND: The functional polymorphism -260 C>T in the LPS sensing TLR4 co-receptor CD14 gene enhances the transcriptional activity and results in a higher CD14 receptor density. Individuals carrying the T/T genotype also have significantly higher serum levels of soluble CD14. The T allele of th...
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