Article
Cold shock proteins contribute to the regulation of listeriolysin O production in Listeria monocytogenes.
Foodborne pathogens and disease - 1 Dec 2013
Schärer Kerstin, Stephan Roger, Tasara Taurai
Abstract excerpt
Cold shock proteins (Csps) are multifunctional nucleic acid binding proteins used to regulate a wide range of gene expression responses in bacteria. We report here that Csps regulate the production of the pore-forming cytolysin listeriolysin (LLO) and hemolysis phenotypes in Listeria monocytogenes. A triple csp gene deletion mutant incapable of producing any Csps, as well as double csp gene deletion mutants only...
Topics
- Bacterial Proteins
- Bacterial Toxins
- Cold Shock Proteins and Peptides
- Gene Deletion
- Gene Expression Regulation, Bacterial
- Heat-Shock Proteins
- Hemolysin Proteins
- Hemolysis
- Listeria monocytogenes
- Listeriosis
- Mutation
- Phenotype
- RNA Stability
- RNA, Messenger
- Virulence
- Virulence Factors