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Article

Definition of progression risk based on combinations of cellular and molecular markers in patients with Binet stage A chronic lymphocytic leukaemia.

British journal of haematology - 1 Jun 2009

Morabito Fortunato, Cutrona Giovanna, Gentile Massimo, Matis Serena, Todoerti Katia, Colombo Monica, Sonaglio Claudia, Fabris Sonia, Reverberi Daniele, Megna Mauro, Spriano Mauro, Lucia Eugenio, Rossi Edoardo, Callea Vincenzo, Mazzone Carla, Festini Gianluca, Zupo Simonetta, Molica Stefano, Neri Antonino, Ferrarini Manlio

Abstract excerpt

IGHV mutational status and ZAP-70 or CD38 expression correlate with clinical course in B-cell chronic lymphocytic leukaemia (CLL). The three markers may be discordant in the single case and there is no consensus on their combined use in clinical practise. This multicenter study investigated this...

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Share to ADP-ribosyl Cyclase 1
Share to Genes, Immunoglobulin Heavy Chain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin Variable Region

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Oligonucleotide Array Sequence Analysis

Share to Proportional Hazards Models

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Share to ZAP-70 Protein-Tyrosine Kinase

Source

Identifiers

PMID: 19438486
DOI: 10.1111/j.1365-2141.2009.07703.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19438486-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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