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Article

Structural and kinetic analyses of the H121A mutant of cholesterol oxidase.

The Biochemical journal - 15 Nov 2006

Lim Louis, Molla Gianluca, Guinn Nicole, Ghisla Sandro, Pollegioni Loredano, Vrielink Alice

Abstract excerpt

Cholesterol oxidase is a monomeric flavoenzyme that catalyses the oxidation of cholesterol to cholest-5-en-3-one followed by isomerization to cholest-4-en-3-one. The enzyme from Brevibacterium sterolicum contains the FAD cofactor covalently bound to His121. It was previously demonstrated that the...

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Identifiers

PMID: 16856877
DOI: 10.1042/BJ20060664
PMCID: PMC1635447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16856877-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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