Article
[Genetics of heteroplasmy in the mtDNA control region among the Chinese Han population].
Fa yi xue za zhi - 1 Jun 2006
Jiang Qiong-Cheng, Tong Da-Yue, Sun Hong-Yu, Ou Jing-Hua, Chen Li-Xian, Wu Xin-Yao
Abstract excerpt
OBJECTIVE: To explore the distribution and genetic pattern of heteroplasmy of mtDNA control region among Chinese Han population. METHODS: The human mtDNA control region was amplified into 6 amplicons overlapped partially each other. Then these amplicons were analyzed by DHPLC which we developed to detect low heteroplasmic signals. RESULTS: There were 51 heteroplasmic cases (34%) found from different tissues of...
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