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Article

Recent Advances in Detecting Mitochondrial DNA Heteroplasmic Variations.

Molecules (Basel, Switzerland) - 3 Feb 2018

Duan Mengqin, Tu Jing, Lu Zuhong

Abstract excerpt

The co-existence of wild-type and mutated mitochondrial DNA (mtDNA) molecules termed heteroplasmy becomes a research hot point of mitochondria. In this review, we listed several methods of mtDNA heteroplasmy research, including the enrichment of mtDNA and the way of calling heteroplasmic variations. At the present, while calling the novel ultra-low level heteroplasmy, high-throughput sequencing method is dominant...

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Share to Centrifugation, Density Gradient
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to High-Throughput Nucleotide Sequencing

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Identifiers

PMID: 29401641
DOI: 10.3390/molecules23020323
PMCID: PMC6017848

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