Occurrence and stability of insertion sequences in Mycobacterium tuberculosis complex strains: evaluation of an insertion sequence-dependent DNA polymorphism as a tool in the epidemiology of tuberculosis

Abstract excerpt

In this study we established the usefulness of DNA fingerprinting for the epidemiology of tuberculosis on the basis of the DNA polymorphism generated by the insertion sequence (IS) IS986. Although clinical isolates of Mycobacterium tuberculosis displayed a remarkably high degree of restriction fragment length polymorphism, we showed that transposition of this IS element is an extremely rare event in M....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Mycobacterium research and diagnosis
• Share to RNA and protein synthesis mechanisms
• Share to Tuberculosis Research and Epidemiology