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Article

In Vivo IS6110 Profile Changes in a Mycobacterium tuberculosis Strain as Determined by Tracking over 14 Years.

Journal of clinical microbiology - 1 Jul 2015

Millán-Lou María Isabel, Otal Isabel, Monforte María Luisa, Vitoria María Asunción, Revillo María José, Martín Carlos, Samper Sofía

Abstract excerpt

Transposition and homologous recombination of IS6110 appear in Mycobacterium tuberculosis along in vivo sequential infections. These events were checked in different clones of a successful strain, M. tuberculosis Zaragoza, with the focus on a variant in which integration of a copy of IS6110 in the origin of replication (oriC) region occurred.

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Identifiers

PMID: 25948604
DOI: 10.1128/JCM.00607-15
PMCID: PMC4473185

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