Article
Use of genetic distance as a measure of ongoing transmission of Mycobacterium tuberculosis.
Journal of clinical microbiology - 1 Dec 2003
van der Spuy G D, Warren R M, Richardson M, Beyers N, Behr M A, van Helden P D
Abstract excerpt
The stability of the genotypic marker IS6110, used to define the epidemiology of Mycobacterium tuberculosis, is one of the most important factors influencing the interpretation of DNA fingerprint data. We propose that evolved strains should be considered together with clustered strains to represent chains of ongoing transmission. For the present study we used a large set of fingerprint data for strains collected...
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