Article
Bax deletion does not protect neurons from BSE-induced death.
Neurobiology of disease - 1 Sept 2006
Coulpier Muriel, Messiaen Sébastien, Hamel Rodolphe, Fernández de Marco Mar, Lilin Thomas, Eloit Marc
Abstract excerpt
Neurodegeneration is a common neuropathological feature of prion diseases. Although evidence of apoptosis was found in natural and experimental prion diseases, the precise mechanisms by which neurons die are poorly understood. The pro-apoptotic BAX protein, a key factor of the mitochondrial pathw...
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