Article
Apoptosis in experimental rabies in bax-deficient mice.
Acta neuropathologica - 1 Sept 1999
Jackson A C
Abstract excerpt
The challenge virus standard (CVS) of fixed rabies virus produces a fatal encephalitis in adult and suckling mice after intracerebral inoculation. The infection is associated with apoptotic cell death in brain neurons and increased immunoreactivity to the Bax protein in the hippocampus and cerebral cortex. Five- to 7-day-old bax-deficient mice and their wild-type littermates were inoculated intracerebrally with...
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