Article
(De)constructing the ryanodine receptor: modeling ion permeation and selectivity of the calcium release channel.
The journal of physical chemistry. B - 18 Aug 2005
Gillespie Dirk, Xu Le, Wang Ying, Meissner Gerhard
Abstract excerpt
Biological ion channels are proteins that passively conduct ions across membranes that are otherwise impermeable to ions. Here, we present a model of ion permeation and selectivity through a single, open ryanodine receptor (RyR) ion channel. Combining recent mutation data with electrodiffusion of...
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