Article
Role of genotype and dopamine receptors in behaviour of inbred mice in a forced swimming test.
Psychopharmacology - 1 Jan 1991
Nikulina E M, Skrinskaya J A, Popova N K
Abstract excerpt
The role of genotype in the effects of selective D1 and D2 dopamine agonists and antagonists on behavioural despair (Porsolt's test) was studied. Mice of nine inbred strains showed significant interstrain differences in duration of immobility. The influence of dopaminergic drugs was assessed in six strains characterized by different levels of swimming activity. SKF 38393 (10 mg/kg), an agonist at D1 dopamine...
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