Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Curcumin Affects Components of the Chromosomal Passenger Complex and Induces Mitotic Catastrophe in Apoptosis-Resistant Bcr-Abl-Expressing Cells

1 Jul 2006

Abstract excerpt

The Bcr-Abl oncoprotein plays a major role in the development and progression of chronic myeloid leukemia and is a determinant of chemotherapy resistance occurring during the blast crisis phase of the disease. The aim of this article was to investigate the possibility of combating the resistance to apoptosis caused by Bcr-Abl by inducing an alternative cell death process. As a model of chronic myeloid leukemia,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Lymphocytic Leukemia Research
Share to Chronic Myeloid Leukemia Treatments
Share to Retinoids in leukemia and cellular processes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16849521
DOI: 10.1158/1541-7786.mcr-05-0172

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Curcumin Affects Components of the Chromosomal Passenger Complex and Induces Mitotic Catastrophe in Apoptosis-Resistant Bcr-Abl-Expressing CellsPMID 16849521Read ↗

BCR-ABL-mediated inhibition of apoptosis with delay of G2/M transition after DNA damage: a mechanism of resistance to multiple anticancer agentsSemantic proximity Read ↗

Anti cancer effects of curcumin: cycle of life and deathSemantic proximity Read ↗

Antimetabolites: Established cancer therapySemantic proximity Read ↗

Mitotic catastrophe and cancer drug resistance: A link that must to be broken.Semantic proximity Read ↗

p53 stabilization induces apoptosis in chronic myeloid leukemia blast crisis cells.Semantic proximity Read ↗

Anaphase-promoting complex/cyclosome protein Cdc27 is a target for curcumin-induced cell cycle arrest and apoptosisSemantic proximity Read ↗

Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemiaSemantic proximity Read ↗

PBA2, a novel inhibitor of the β-catenin/CBP pathway, eradicates chronic myeloid leukemia including BCR-ABL T315I mutation.Semantic proximity Read ↗

Bcl-xL controls a switch between cell death modes during mitotic arrestSemantic proximity Read ↗

BCR-ABL: a multi-faceted promoter of DNA mutation in chronic myelogeneous leukemia.Semantic proximity Read ↗

Mechanisms of drug-induced mitotic catastrophe in cancer cells.Semantic proximity Read ↗

Inhibition of mitochondrial metabolism by methyl-2-cyano-3,12-dioxooleana-1,9-diene-28-oate induces apoptotic or autophagic cell death in chronic myeloid leukemia cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.