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Article

Cutting edge: lupus susceptibility interval Sle3/5 confers responsiveness to prolactin in C57BL/6 mice.

Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 2006

Peeva Elena, Gonzalez Juana, Hicks Ruthmarie, Diamond Betty

Abstract excerpt

Prolactin is of interest in the pathogenesis of systemic lupus erythematosus (SLE) because almost 25% of SLE patients display hyperprolactinemia, and serum prolactin correlates with disease activity in some patients. Furthermore, hyperprolactinemia causes early mortality in lupus-prone mice and induces a lupus-like phenotype in nonspontaneously autoimmune mice. We show here that the immunomodulatory effects of...

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Source

Identifiers

PMID: 16849443
DOI: 10.4049/jimmunol.177.3.1401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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