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Article

Use of chemical mutagenesis in mouse embryonic stem cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2006

Becker Sonja, de Angelis Martin Hrabé, Beckers Johannes

Abstract excerpt

The chemical mutagenesis of mouse embryonic stem (ES) cells is an approach complementary to chemical mutagenesis of spermatogonia in whole animals. It has great potential to contribute significantly to the generation of a comprehensive collection of multiple alleles for most mammalian genes and to facilitate the progression from gene sequence to gene functional analyses. The general strategy includes the...

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PMID: 16846006
DOI: 10.1385/1-59745-037-5:397

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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