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Article

Molecular characteristics of porcine alpha-synuclein splicing variants.

Biochimie - 1 Jan 2021

Larsen Knud, Bæk Rikke, Sahin Cagla, Kjær Lars, Christiansen Gunna, Nielsen Janni, Farajzadeh Leila, Otzen Daniel E

Abstract excerpt

Alpha-synuclein (α-syn) is a 140 amino acid, intrinsically disordered protein with a potential role in neurotransmitter vesicle release. The protein is natively unfolded under physiological conditions, and is expressed predominantly in neural tissue. α-syn is associated with neuropathological conditions in Parkinson's disease, where the protein misfolds into oligomers and fibrils resulting in aggregates in Lewy...

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PMID: 33152422
DOI: 10.1016/j.biochi.2020.10.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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