Article
Restriction isotyping of human apolipoprotein A-IV: rapid typing of known isoforms and detection of a new isoform that deletes a conserved repeat.
Journal of lipid research - 1 Sept 1991
Hixson J E, Powers P K
Abstract excerpt
Genetic polymorphisms of apolipoprotein A-IV (apoA-IV) have been detected by isoelectric focusing of serum proteins. Because genetic variation in apoA-IV has significant effects on lipid risk factors, we used restriction enzyme isoform genotyping (restriction isotyping) to determine apoA-IV isoform genotypes at the DNA level for a large population (n = 509). In contrast to isoelectric focusing methods,...
Topics
- Adolescent
- Adult
- Alleles
- Amino Acid Sequence
- Apolipoproteins A
- Base Sequence
- Chromosome Deletion
- DNA
- Genetic Techniques
- Genotype
- Humans
- Male