Article
Two common polymorphisms in the APO A-IV coding gene: their evolution and linkage disequilibrium.
Genetic epidemiology - 1 Jan 1992
Kamboh M I, Hamman R F, Ferrell R E
Abstract excerpt
Human apolipoprotein A-IV (APO A-IV) exhibits a common protein polymorphism detectable by isoelectric focusing (IEF) due to a single base substitution at codon 360 which replaces the frequently occurring glutamine residue (allele 1) with histidine (allele 2). Recently, sequence analysis of the AP...
Topics
- Apolipoproteins A
- Base Sequence
- Biological Evolution
- Codon
- DNA
- Genes
- Genetic Variation
- Genotype
- Haplotypes
- Humans
- Linkage Disequilibrium
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Genetic