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Article

Functional characterization of new allelic polymorphisms identified in the promoter region of the human MxA gene.

International journal of immunogenetics - 1 Aug 2013

Tran Thi Duc T, Desmecht D, Cornet A

Abstract excerpt

The Mx proteins are high-molecular-weight dynamin-like proteins whose expression depends strictly on type-I and type-III interferons (IFN). Some isoforms are able to inhibit the life cycle of one or several viruses and are thus components of innate immune response. The human MxA protein displays the broadest antiviral spectrum which makes it appear as a key antiviral effector of innate immunity. Allelic...

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PMID: 22985419
DOI: 10.1111/j.1744-313X.2012.01153.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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