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Article

Roles of organizer factors and BMP antagonism in mammalian forebrain establishment.

Developmental biology - 15 Aug 2006

Yang Yu-Ping, Klingensmith John

Abstract excerpt

A critical question in mammalian development is how the forebrain is established. In amphibians, bone morphogenetic protein (BMP) antagonism emanating from the gastrula organizer is key. Roles of BMP antagonism and the organizer in mammals remain unclear. Anterior visceral endoderm (AVE) promotes early mouse head development, but its function is controversial. Here, we explore the timing and regulation of...

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Identifiers

PMID: 16839541
DOI: 10.1016/j.ydbio.2006.06.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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