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Article

Genetic polymorphisms at FCER1B and PAI-1 and asthma susceptibility.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jul 2006

Hizawa N, Maeda Y, Konno S, Fukui Y, Takahashi D, Nishimura M

Abstract excerpt

BACKGROUND: We previously detected a promoter polymorphism (- 109C/T) in the gene for the beta-chain of the high-affinity receptor for IgE (FCER1B), which was associated with total serum IgE levels but not with asthma in a Japanese population. A genetic interaction is biologically plausible between FcepsilonRI-beta and the plasminogen activator inhibitor 1 (PAI-1), which is highly expressed in mast cells in...

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Source

Identifiers

PMID: 16839401
DOI: 10.1111/j.1365-2222.2006.02413.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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