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Article

Rapid genetic analysis of families with polycystic kidney disease 1 by means of a microsatellite marker.

Lancet (London, England) - 14 Dec 1991

Harris P C, Thomas S, Ratcliffe P J, Breuning M H, Coto E, Lopez-Larrea C

Abstract excerpt

Presymptomatic diagnosis of polycystic kidney disease 1 (PKD1) is possible by genetic linkage analysis with markers from both sides of the disease locus. The existing proximal markers are not informative in many families, so such analysis is difficult and time-consuming. We sought more useful length polymorphisms on the proximal side of the locus among simple sequence repeats (microsatellites). We identified two...

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Source

Identifiers

PMID: 1683919
DOI: 10.1016/0140-6736(91)92300-q

Genes

PKD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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