Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic heterogeneity in adult dominant polycystic kidney disease in Cypriot families.

Human genetics - 1 Apr 1995

Constantinou-Deltas C D, Papageorgiou E, Boteva K, Christodoulou K, Breuning M H, Peter D J, Pierides A

Abstract excerpt

Polycystic kidney disease is an inherited heterogeneous disorder that affects approximately 1:1000 Europeans. It is characterized mainly by the formation of cysts in the kidney that lead to end-stage renal failure with late age of onset. Three loci have been identified, PKD1 on the short arm of chromosome 16, which has recently been isolated and characterized, PKD2 on the long arm of chromosome 4, and a third...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to DNA
Share to DNA Probes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Linkage

Share to Genetic Markers

Share to Pedigree

Share to Phenotype

Source

Identifiers

PMID: 7705838
DOI: 10.1007/BF00208967

Genes

PKD1
PKD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic heterogeneity in adult dominant polycystic kidney disease in Cypriot families.PMID 7705838Read ↗

Presymptomatic molecular diagnosis of autosomal dominant polycystic kidney disease using PKD1- and PKD2-linked markers in Cypriot families.Semantic proximity Read ↗

Molecular genetics of autosomal dominant polycystic kidney disease.Semantic proximity Read ↗

Determinants of renal disease variability in ADPKD.Semantic proximity Read ↗

The genetic landscape of polycystic kidney disease in Ireland.Semantic proximity Read ↗

Mutations of the human polycystic kidney disease 2 (PKD2) gene.Semantic proximity Read ↗

Co-Inheritance of Pathogenic Variants in PKD1 and PKD2 Genes Determined by Parental Segregation and De Novo Origin: A Case Report.Semantic proximity Read ↗

Genotype-phenotype of autosomal dominant polycystic kidney disease in Malta.Semantic proximity Read ↗

Hypomorphic PKD1 Alleles Impact Disease Variability in Autosomal Dominant Polycystic Kidney Disease.Semantic proximity Read ↗

Genetic heterogeneity of polycystic kidney disease in Europe.Semantic proximity Read ↗

Genetic heterogeneity of polycystic kidney disease in Bulgaria.Semantic proximity Read ↗

Co-inheritance of a PKD1 mutation and homozygous PKD2 variant: a potential modifier in autosomal dominant polycystic kidney disease.Semantic proximity Read ↗

Refining genotype-phenotype correlations in 304 patients with autosomal recessive polycystic kidney disease and PKHD1 gene variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.