Genetic heterogeneity in adult dominant polycystic kidney disease in Cypriot families.

doi:10.1007/BF00208967

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Article

Genetic heterogeneity in adult dominant polycystic kidney disease in Cypriot families.

Human genetics - 1 Apr 1995

Constantinou-Deltas C D, Papageorgiou E, Boteva K, Christodoulou K, Breuning M H, Peter D J, Pierides A

Abstract excerpt

Polycystic kidney disease is an inherited heterogeneous disorder that affects approximately 1:1000 Europeans. It is characterized mainly by the formation of cysts in the kidney that lead to end-stage renal failure with late age of onset. Three loci have been identified, PKD1 on the short arm of c...

Topics

Aged
Cyprus
DNA
DNA Probes
Female
Gene Frequency
Genetic Heterogeneity
Genetic Linkage
Genetic Markers
Humans
Male
Middle Aged
Pedigree
Phenotype
Polycystic Kidney, Autosomal Dominant

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