Article
Contrasting signatures of selection on the Plasmodium falciparum erythrocyte binding antigen gene family.
Molecular and biochemical parasitology - 1 Oct 2006
Verra Federica, Chokejindachai Watcharee, Weedall Gareth D, Polley Spencer D, Mwangi Tabitha W, Marsh Kevin, Conway David J
Abstract excerpt
Erythrocyte binding antigens of Plasmodium falciparum are involved in erythrocyte invasion, and may be targets of acquired immunity. Of the five eba genes, protein products have been detected for eba-175, eba-181 and eba-140, but not for psieba-165 or ebl-1, providing opportunity for comparative analysis of genetic variation to identify selection. Region II of each of these genes was sequenced from a...
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