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Article

Multiplex single nucleotide polymorphism genotyping by adapter ligation-mediated allele-specific amplification.

Analytical biochemistry - 15 Aug 2006

Wang Wei-peng, Ni Kun-yi, Zhou Guo-hua

Abstract excerpt

An improved approach for increasing the multiplex level of single nucleotide polymorphism (SNP) typing by adapter ligation-mediated allele-specific amplification (ALM-ASA) has been developed. Based on an adapter ligation, each reaction requires n allele-specific primers plus an adapter-specific primer that is common for all SNPs. Thus, only n+1 primers are used for an n-plex PCR amplification. The specificity of...

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PMID: 16836969
DOI: 10.1016/j.ab.2006.04.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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